Accuracy of First and Second Generation Testosterone Assays and Improvement through Sample Extraction

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چکیده

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Accuracy of First and Second Generation Testosterone Assays and Improvement through Sample Extraction

Employment or Leadership: None declared. Consultant or Advisory Role: None declared. Stock Ownership: None declared. Honoraria: None declared. Research Funding: R. Ensenauer, German Federal Ministry of Education and Research (BMBF) grant no. 0315088; J. Gmach, German Federal Ministry of Education and Research (BMBF) grant no. 0315088; Ina Nehring, German Federal Ministry of Education and Resear...

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Accuracy of first and second generation testosterone assays and improvement through sample extraction.

The monitoring of antiandrogen treatment in patients with prostate cancer, investigation of hyperandrogenism in women, and evaluation of infants with ambiguous genitalia require accurate measurement of low testosterone concentrations. However, testosterone immunoassays have been shown to be inaccurate and often to overestimate testosterone concentrations in the low range (1 ). A working group o...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2012

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2011.181735